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In contrast to their expectations, the results have shown that daily supplementation with vitamin C and vitamin A for 4 weeks not only failed to improve the insulin responsiveness but also decreased the expression of ROS-sensitive transcriptional regulators, molecular mediators of ROS defense (SOD 1 and 2, glutathione peroxidase) [90]

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The simulated results of molecular docking indicated that GHK-Cu can directly bind to SIRT1 to form a protein complex, and the interacting residues in the complex are composed of GLU-230 and ASN-226 (Figure 5E)

Similar content being viewed by others Introduction Aging is characterized by a progressive loss of physiological integrity and function of organs and organisms

Since NZs are less expensive, more easily produced, and more stable than natural enzymes, they hold great promise for use in various applications, including treating microbial infections